Catacombs of Domitilla, also called Catacombe di Santa Domitilla or Catacombs of Saint Domitilla, stretch below Via delle Sette Chiese in south Rome, where a late 4th-century AD basilica, vivid frescoes, and the old Flavian Hypogeum make this underground site feel richer and more atmospheric than a simple corridor visit.
Start with a guided tour that includes transfer if you want the easiest first visit, because Domitilla sits off the standard center-city route and the best products remove the logistics.